STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARIH2RBR-type E3 ubiquitin transferase. (491 aa)    
Predicted Functional Partners:
CUL5
Cullin-5; Belongs to the cullin family.
    
 0.967
RNF7
RING-box protein 2.
    
 0.893
EIF2B5
LOW QUALITY PROTEIN: translation initiation factor eIF-2B subunit epsilon.
 
 
    0.837
NEDD8
NEDD8.
   
 0.826
RAD23A
UV excision repair protein RAD23 homolog A.
   
 0.663
IKBKG
NF-kappa-B essential modulator.
    
 0.628
TNF
Tumor necrosis factor; Belongs to the tumor necrosis factor family.
   
 0.612
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.611
RPS27A
ubiquitin-40S ribosomal protein S27a.
   
 0.609
ASB13
Ankyrin repeat and SOCS box containing 13.
    
 
 0.604
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.