STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRCPLysosomal Pro-X carboxypeptidase. (495 aa)    
Predicted Functional Partners:
MEP1A
Metalloendopeptidase.
     
 0.966
MEP1B
Meprin A subunit.
     
 0.950
MME
Neprilysin isoform X2.
   
 
 0.949
ACE2
Angiotensin-converting enzyme.
     
 0.937
DPP4
Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.
     
 0.919
XPNPEP2
xaa-Pro aminopeptidase 2; Belongs to the peptidase M24B family.
   
 
 0.917
SH3BP5
SH3 domain-binding protein 5.
      
 0.773
DHPS
Deoxyhypusine synthase.
      
 0.728
GALNS
Galactosamine (N-acetyl)-6-sulfatase.
   
 
 0.704
F3
Tissue factor.
      
 0.659
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.