STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM126ATransmembrane protein 126A. (197 aa)    
Predicted Functional Partners:
TMEM109
Transmembrane protein 109.
      
 0.838
SEC11C
Signal peptidase complex catalytic subunit SEC11.
   
  
 0.784
TMEM41A
Transmembrane protein 41A isoform X1.
      
 0.783
NDUFAF1
Complex I intermediate-associated protein 30, mitochondrial.
   
 
 0.775
MARCHF5
Membrane associated ring-CH-type finger 5.
      
 0.748
RTN4IP1
Reticulon-4-interacting protein 1, mitochondrial isoform X1.
   
  
 0.740
ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform X1.
     
 0.735
TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1.
      
 0.725
APOO
MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
   
   0.702
ACADVL
LOW QUALITY PROTEIN: very long-chain specific acyl-CoA dehydrogenase, mitochondrial.
   
 
 0.690
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.