STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOX4NADPH oxidase 4. (578 aa)    
Predicted Functional Partners:
LOC103673846
Cytochrome b-245 light chain.
   
 0.998
NOX1
NADPH oxidase 1 isoform X1.
  
 
0.985
CYBB
Cytochrome b-245 heavy chain.
  
 
0.982
NCF2
Neutrophil cytosol factor 2.
   
 0.913
NCF1
Neutrophil cytosol factor 1.
   
 0.904
XK
XK-related protein.
 
  
 0.825
NOX5
NADPH oxidase 5.
     
0.824
TLR4
Toll-like receptor 4; Belongs to the Toll-like receptor family.
   
 
 0.822
NOX3
NADPH oxidase 3.
  
 
0.805
POLDIP2
DNA polymerase delta interacting protein 2.
      
 0.725
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.