STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRICKLE1Prickle-like protein 1. (804 aa)    
Predicted Functional Partners:
VANGL2
Vang-like protein.
    
 0.986
VANGL1
Vang-like protein.
    
 0.986
DVL3
Segment polarity protein dishevelled homolog DVL-3.
    
 0.961
DVL2
LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-2.
    
 0.905
PRICKLE4
Prickle-like protein 4.
     
0.900
LOC103682075
Segment polarity protein dishevelled homolog DVL-1-like.
    
 0.869
FZD3
Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.815
SMURF2
E3 ubiquitin-protein ligase.
    
 0.734
FZD6
Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.
  
 
 0.723
INVS
Inversin isoform X1.
   
 0.638
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.