STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSUMAP00000034288annotation not available (194 aa)    
Predicted Functional Partners:
DOCK5
LOW QUALITY PROTEIN: dedicator of cytokinesis protein 5; Belongs to the DOCK family.
 
   
  0.911
ELMO1
Engulfment and cell motility protein 1 isoform X1.
    
 0.840
RAC2
Ras-related C3 botulinum toxin substrate 2.
   
 0.764
PTPRC
Receptor-type tyrosine-protein phosphatase C isoform X1.
   
  
 0.721
CRK
Adapter molecule crk.
    
 0.695
DOCK8
Dedicator of cytokinesis protein 8; Belongs to the DOCK family.
   
 
 0.692
ELMO2
Engulfment and cell motility protein 2.
    
 0.688
ELMO3
Engulfment and cell motility protein 3 isoform X1.
    
 0.673
DOCK10
Dedicator of cytokinesis protein 10 isoform X1; Belongs to the DOCK family.
   
 
 0.669
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.657
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.