STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRYAAAlpha-crystallin A chain; Belongs to the small heat shock protein (HSP20) family. (177 aa)    
Predicted Functional Partners:
CRYAB
Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
  
 
0.980
CRYBA1
Beta-crystallin A3; Belongs to the beta/gamma-crystallin family.
   
 
 0.947
CRYBA2
Beta-crystallin A2; Belongs to the beta/gamma-crystallin family.
   
  
 0.899
CRYBB2
Crystallin beta B2; Belongs to the beta/gamma-crystallin family.
   
 
 0.885
CRYBB3
LOW QUALITY PROTEIN: beta-crystallin B3; Belongs to the beta/gamma-crystallin family.
   
  
 0.857
CRYGS
Beta-crystallin S isoform X1; Belongs to the beta/gamma-crystallin family.
   
 
 0.790
CRYBB1
LOW QUALITY PROTEIN: beta-crystallin B1; Belongs to the beta/gamma-crystallin family.
   
  
 0.763
CRYGC
Gamma-crystallin C isoform X1; Belongs to the beta/gamma-crystallin family.
   
 
 0.701
GJA8
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
   
  
 0.693
CRYBA4
Beta-crystallin A4 isoform X1; Belongs to the beta/gamma-crystallin family.
   
 
 0.683
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.