STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LIN7BProtein lin-7 homolog B isoform X1. (259 aa)    
Predicted Functional Partners:
CASK
Peripheral plasma membrane protein CASK; Belongs to the MAGUK family.
    
0.977
MOCS3
Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
    
 0.813
PRDX5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.796
MPP1
55 kDa erythrocyte membrane protein isoform X1; Belongs to the MAGUK family.
    
 0.794
RTKN
Rhotekin isoform X1.
     
 0.786
APBA1
Amyloid beta A4 precursor protein-binding family A member 1.
    
 0.706
MPP2
MAGUK p55 subfamily member 2 isoform X1; Belongs to the MAGUK family.
    
 0.682
MPP6
MAGUK p55 subfamily member 6 isoform X1; Belongs to the MAGUK family.
    
 0.682
DLG5
Disks large homolog 5 isoform X1; Belongs to the MAGUK family.
   
0.657
CAMK2D
Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X4.
    
 0.653
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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