STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CARD8Caspase recruitment domain-containing protein 8. (496 aa)    
Predicted Functional Partners:
DPP9
Dipeptidyl peptidase 9 isoform X4; Belongs to the peptidase S9B family.
    
 
 0.841
NLRP3
NACHT, LRR and PYD domains-containing protein 3.
 
 
 0.806
NLRP10
LOW QUALITY PROTEIN: NACHT, LRR and PYD domains-containing protein 10.
 
 
 0.805
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.798
APPL2
DCC-interacting protein 13-beta isoform X1.
    
 0.783
APPL1
DCC-interacting protein 13-alpha isoform X1.
    
 0.783
CASP9
Caspase-9; Belongs to the peptidase C14A family.
    
 0.675
BIRC6
Baculoviral IAP repeat-containing protein 6.
   
 0.674
LOC110589905
Apoptosis-associated speck-like protein containing a CARD.
    
 0.627
DPP8
Dipeptidyl peptidase 8; Belongs to the peptidase S9B family.
    
 
 0.605
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.