STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL12Kelch-like protein 12. (568 aa)    
Predicted Functional Partners:
CUL3
Cullin-3 isoform X1; Belongs to the cullin family.
    
 0.985
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.905
DVL1
Segment polarity protein dishevelled homolog DVL-1 isoform X1.
    
 0.872
PEF1
Peflin.
    
 
 0.784
SEC31A
Protein transport protein Sec31A isoform X1.
    
 
 0.730
DVL3
Segment polarity protein dishevelled homolog DVL-3 isoform X1.
    
 0.702
DVL2
Segment polarity protein dishevelled homolog DVL-2.
    
 0.691
SEC22B
Vesicle-trafficking protein SEC22b; Belongs to the synaptobrevin family.
      
 0.614
CUL1
Cullin-1 isoform X1; Belongs to the cullin family.
    
 0.608
SEC16B
Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
    
 
 0.588
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.