STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPCSPhosphopantothenate--cysteine ligase isoform X1. (310 aa)    
Predicted Functional Partners:
PANK3
Pantothenate kinase 3.
     
 0.979
COASY
Bifunctional coenzyme A synthase isoform X1.
  
 0.965
PPCDC
Phosphopantothenoylcysteine decarboxylase isoform X1.
    
 0.961
PANK2
LOW QUALITY PROTEIN: pantothenate kinase 2, mitochondrial.
     
 0.957
PANK4
4'-phosphopantetheine phosphatase; May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'- phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway.
     
 0.939
PANK1
LOW QUALITY PROTEIN: pantothenate kinase 1.
     
 0.925
CTH
Cystathionine gamma-lyase.
   
 
  0.883
KYAT3
Kynurenine--oxoglutarate transaminase 3 isoform X4.
  
  0.862
KYAT1
Kynurenine--oxoglutarate transaminase 1 isoform X1.
  
  0.843
HLCS
Biotin--protein ligase.
  
 
 0.795
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.