STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)    
Predicted Functional Partners:
CDK4
Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.
   
 0.999
CDK6
Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.999
CDK2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.997
CDKN1A
Cyclin-dependent kinase inhibitor 1.
   
 0.996
RB1
Retinoblastoma-associated protein.
    
 0.990
GSK3B
Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.
    
 0.974
CDKN1C
Cyclin-dependent kinase inhibitor 1C.
   
 0.966
CDKN1B
Cyclin-dependent kinase inhibitor 1B.
   
 0.966
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.964
RBL2
Retinoblastoma-like protein 2 isoform X1.
    
 0.956
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.