STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIF12Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (656 aa)    
Predicted Functional Partners:
PLG
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
   
  
 0.953
KIFAP3
Kinesin-associated protein 3.
   
 0.837
PAH
Phenylalanine-4-hydroxylase.
      
 0.734
CCHCR1
Coiled-coil alpha-helical rod protein 1 isoform X1.
      
 0.678
LUC7L
Putative RNA-binding protein Luc7-like 1 isoform X4.
      
 0.667
ZFYVE19
abscission/NoCut checkpoint regulator.
      
 0.613
ZW10
Centromere/kinetochore protein zw10 homolog.
     
 0.587
ARF5
ADP-ribosylation factor 5; Belongs to the small GTPase superfamily. Arf family.
    
  0.568
RAB19
Ras-related protein Rab-19.
     
 0.546
RAB43
Ras-related protein Rab-43 isoform X1.
     
 0.546
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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