STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OSGEPProbable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. (335 aa)    
Predicted Functional Partners:
TP53RK
TP53-regulating kinase.
  
 0.994
TPRKB
EKC/KEOPS complex subunit TPRKB; Belongs to the CGI121/TPRKB family.
    
 0.994
GON7
EKC/KEOPS complex subunit GON7.
    
 0.951
YRDC
yrdC domain-containing protein, mitochondrial.
  
 
 0.946
CCNB1IP1
E3 ubiquitin-protein ligase CCNB1IP1.
      
 0.740
DCAKD
dephospho-CoA kinase domain-containing protein.
    
 0.728
COASY
Bifunctional coenzyme A synthase isoform X1.
    
 0.728
LOC110576826
Low molecular weight phosphotyrosine protein phosphatase-like.
    
  0.727
ACP1
Low molecular weight phosphotyrosine protein phosphatase isoform X1.
    
  0.727
PUDP
Pseudouridine-5'-phosphatase.
    
 0.687
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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