node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACP1 | OSGEP | A0A2Y9HMV0 | A0A2Y9HHI5 | Low molecular weight phosphotyrosine protein phosphatase isoform X1. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.727 |
ACP1 | PUDP | A0A2Y9HMV0 | A0A2Y9GEU3 | Low molecular weight phosphotyrosine protein phosphatase isoform X1. | Pseudouridine-5'-phosphatase. | 0.527 |
CCNB1IP1 | OSGEP | A0A2Y9HNS2 | A0A2Y9HHI5 | E3 ubiquitin-protein ligase CCNB1IP1. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.740 |
COASY | DCAKD | A0A2Y9GE75 | A0A2Y9GDY5 | Bifunctional coenzyme A synthase isoform X1. | dephospho-CoA kinase domain-containing protein. | 0.901 |
COASY | OSGEP | A0A2Y9GE75 | A0A2Y9HHI5 | Bifunctional coenzyme A synthase isoform X1. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.728 |
DCAKD | COASY | A0A2Y9GDY5 | A0A2Y9GE75 | dephospho-CoA kinase domain-containing protein. | Bifunctional coenzyme A synthase isoform X1. | 0.901 |
DCAKD | OSGEP | A0A2Y9GDY5 | A0A2Y9HHI5 | dephospho-CoA kinase domain-containing protein. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.728 |
GON7 | OSGEP | A0A2Y9GB48 | A0A2Y9HHI5 | EKC/KEOPS complex subunit GON7. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.951 |
GON7 | TP53RK | A0A2Y9GB48 | A0A2Y9H0G4 | EKC/KEOPS complex subunit GON7. | TP53-regulating kinase. | 0.863 |
GON7 | TPRKB | A0A2Y9GB48 | A0A2Y9HZT6 | EKC/KEOPS complex subunit GON7. | EKC/KEOPS complex subunit TPRKB; Belongs to the CGI121/TPRKB family. | 0.540 |
GON7 | YRDC | A0A2Y9GB48 | A0A2Y9GRE9 | EKC/KEOPS complex subunit GON7. | yrdC domain-containing protein, mitochondrial. | 0.538 |
LOC110576826 | OSGEP | A0A2Y9GV27 | A0A2Y9HHI5 | Low molecular weight phosphotyrosine protein phosphatase-like. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.727 |
LOC110576826 | PUDP | A0A2Y9GV27 | A0A2Y9GEU3 | Low molecular weight phosphotyrosine protein phosphatase-like. | Pseudouridine-5'-phosphatase. | 0.527 |
OSGEP | ACP1 | A0A2Y9HHI5 | A0A2Y9HMV0 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | Low molecular weight phosphotyrosine protein phosphatase isoform X1. | 0.727 |
OSGEP | CCNB1IP1 | A0A2Y9HHI5 | A0A2Y9HNS2 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | E3 ubiquitin-protein ligase CCNB1IP1. | 0.740 |
OSGEP | COASY | A0A2Y9HHI5 | A0A2Y9GE75 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | Bifunctional coenzyme A synthase isoform X1. | 0.728 |
OSGEP | DCAKD | A0A2Y9HHI5 | A0A2Y9GDY5 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | dephospho-CoA kinase domain-containing protein. | 0.728 |
OSGEP | GON7 | A0A2Y9HHI5 | A0A2Y9GB48 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | EKC/KEOPS complex subunit GON7. | 0.951 |
OSGEP | LOC110576826 | A0A2Y9HHI5 | A0A2Y9GV27 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | Low molecular weight phosphotyrosine protein phosphatase-like. | 0.727 |
OSGEP | PUDP | A0A2Y9HHI5 | A0A2Y9GEU3 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | Pseudouridine-5'-phosphatase. | 0.687 |