STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYO1EUnconventional myosin-Ie; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1108 aa)    
Predicted Functional Partners:
WAS
wiskott-Aldrich syndrome protein.
   
 0.830
WASL
Neural Wiskott-Aldrich syndrome protein.
   
 0.800
WIPF2
WAS/WASL-interacting protein family member 2.
    
 
 0.787
MTPN
Myotrophin.
    
 
 0.742
ACTR2
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 
 0.566
LAPTM5
Lysosomal-associated transmembrane protein 5.
   
  
 0.524
SYNJ2
Synaptojanin-2.
    
 
 0.510
UNC45A
Protein unc-45 homolog A isoform X1.
    
 
 0.509
UNC45B
Protein unc-45 homolog B isoform X1.
    
 
 0.509
INF2
Inverted formin-2.
    
 
 0.506
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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