STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)    
Predicted Functional Partners:
CSNK2A1
Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.
   
 0.987
CSNK2A2
Casein kinase II subunit alpha.
   
 0.984
NFKBIA
NF-kappa-B inhibitor alpha.
    
  0.912
SUPT16H
FACT complex subunit SPT16 isoform X1.
    
  0.909
CTNNB1
Catenin beta-1.
   
 0.906
SSRP1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
  0.906
PRNP
Major prion protein; Belongs to the prion family.
    
  0.906
RRP7A
Ribosomal RNA-processing protein 7 homolog A.
    
 0.881
KLC4
Kinesin light chain 4 isoform X1.
    
 0.851
KLC2
Kinesin light chain 2 isoform X1.
    
 0.846
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.