STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HERC4Probable E3 ubiquitin-protein ligase HERC4 isoform X1. (1049 aa)    
Predicted Functional Partners:
ZMYM5
Zinc finger MYM-type protein 5 isoform X1.
      
 0.727
RCCD1
RCC1 domain-containing protein 1.
    
0.697
ISG15
Ubiquitin-like protein ISG15.
   
 0.652
NCK1
Cytoplasmic protein.
      
 0.618
NCK2
Cytoplasmic protein.
      
 0.618
MRTO4
Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
      
 0.614
TRIP12
E3 ubiquitin-protein ligase TRIP12 isoform X4.
   
 
0.604
MARCH7
E3 ubiquitin-protein ligase MARCH7 isoform X1.
   
 
 0.571
UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme.
    
 0.568
ANKRD46
Ankyrin repeat domain-containing protein 46.
    
 
 0.559
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.