STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPINK1Serine protease inhibitor Kazal-type 1. (79 aa)    
Predicted Functional Partners:
PRSS2
Trypsin-2; Belongs to the peptidase S1 family.
   
 0.928
LOC110582989
Cationic trypsin isoform X1; Belongs to the peptidase S1 family.
   
 0.928
LOC110574688
chymotrypsin-C-like; Belongs to the peptidase S1 family.
   
 0.695
SPINK9
Serine protease inhibitor Kazal-type 9.
      
 0.614
SPINK2
Serine protease inhibitor Kazal-type 2.
  
   
 0.592
LOC110575376
Proproteinase E-like; Belongs to the peptidase S1 family.
   
 0.518
TMPRSS15
Enteropeptidase; Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
    
 0.495
LOC110583368
LOW QUALITY PROTEIN: chymotrypsinogen B-like; Belongs to the peptidase S1 family.
   
 0.490
LOC110594215
Chymotrypsinogen 2; Belongs to the peptidase S1 family.
   
 0.490
LOC110593944
LOW QUALITY PROTEIN: chymotrypsinogen B-like; Belongs to the peptidase S1 family.
   
 0.490
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.