STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phoUPhosphate transport system protein phou; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. (245 aa)    
Predicted Functional Partners:
pstB
Phosphate import ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
  
 0.995
pstA
Phosphate transport system permease protein psta.
 
  
 0.991
pstC
Phosphate transport system permease protein pstc; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
  
 0.935
pstS
Phosphate-binding periplasmic protein psts; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
 
  
 0.828
phoR
Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Positive and negative sensor protein for pho regulon (positive an negative sensor protein for pho regulon phor).
 
   
 0.593
parC
Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
  
 0.564
arcB
Aerobic respiration control sensor protein.
  
  
 0.504
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.484
lepB
Signal peptidase I; Belongs to the peptidase S26 family.
  
    0.475
phoA
Alkaline phosphatase; Belongs to the alkaline phosphatase family.
  
  
 0.473
Your Current Organism:
Photorhabdus asymbiotica
NCBI taxonomy Id: 291112
Other names: ATCC 43950, CIP 106331, DSM 15149, P. asymbiotica, strain 3265-86
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