STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yigBConserved hypothetical protein. (238 aa)    
Predicted Functional Partners:
PAU_03484
Riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.946
ribF
Riboflavin biosynthesis protein; Belongs to the ribF family.
  
 
 0.917
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
     
 0.905
fre
Nad(p)h-flavin reductase (nad(p)h:flavin oxidoreductase).
  
 
 0.903
PAU_00994
Lumazine binding protein, similar to riboflavin synthase; Lumazine protein (LumP) (gene luxL). LumP is a protein that modulates the colour of the bioluminescence emission of bacterial luciferase.
   
 
 0.902
ribE
Riboflavin synthase alpha chain.
   
 
 0.902
hpaC
4-hydroxyphenylacetic acid hydroxylase putative coupling protein.
     
 0.901
nfsA
Subunit of oxygen-insensitive NADPH nitroreductase; Belongs to the flavin oxidoreductase frp family.
    
 0.900
xerC
Tyrosine recombinase xerc; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges t [...]
  
    0.811
yigA
Conserved hypothetical protein.
  
    0.803
Your Current Organism:
Photorhabdus asymbiotica
NCBI taxonomy Id: 291112
Other names: ATCC 43950, CIP 106331, DSM 15149, P. asymbiotica, strain 3265-86
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