node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ODN68353.1 | folB | A9E74_00326 | A9E74_00327 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.980 |
ODN68353.1 | folC | A9E74_00326 | A9E74_00556 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase. | Bifunctional protein FolC; Belongs to the folylpolyglutamate synthase family. | 0.711 |
ODN68353.1 | folP | A9E74_00326 | A9E74_00342 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.866 |
carB | folP | A9E74_00347 | A9E74_00342 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.717 |
carB | ftsH_1 | A9E74_00347 | A9E74_00343 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.693 |
carB | glmM | A9E74_00347 | A9E74_00341 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.653 |
carB | guaB | A9E74_00347 | A9E74_01633 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.775 |
carB | rlmE | A9E74_00347 | A9E74_00344 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.809 |
folB | ODN68353.1 | A9E74_00327 | A9E74_00326 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase. | 0.980 |
folB | folC | A9E74_00327 | A9E74_00556 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Bifunctional protein FolC; Belongs to the folylpolyglutamate synthase family. | 0.842 |
folB | folK | A9E74_00327 | A9E74_01551 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.997 |
folB | folP | A9E74_00327 | A9E74_00342 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.992 |
folB | ftsH_1 | A9E74_00327 | A9E74_00343 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.578 |
folC | ODN68353.1 | A9E74_00556 | A9E74_00326 | Bifunctional protein FolC; Belongs to the folylpolyglutamate synthase family. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase. | 0.711 |
folC | folB | A9E74_00556 | A9E74_00327 | Bifunctional protein FolC; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.842 |
folC | folK | A9E74_00556 | A9E74_01551 | Bifunctional protein FolC; Belongs to the folylpolyglutamate synthase family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.817 |
folC | folP | A9E74_00556 | A9E74_00342 | Bifunctional protein FolC; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.998 |
folK | folB | A9E74_01551 | A9E74_00327 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.997 |
folK | folC | A9E74_01551 | A9E74_00556 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Bifunctional protein FolC; Belongs to the folylpolyglutamate synthase family. | 0.817 |
folK | folP | A9E74_01551 | A9E74_00342 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |