STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sirBSirohydrochlorin ferrochelatase. (122 aa)    
Predicted Functional Partners:
cobB
Cobyrinic acid A,C-diamide synthase.
 
  
 0.751
hemD
Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
    
 0.675
cysH
Thioredoxin-dependent 5'-adenylylsulfate reductase; Reduction of activated sulfate into sulfite.
 
  
 0.567
ODN67393.1
Ferredoxin, 2Fe-2S.
    
  0.543
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
     
 0.539
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
     
 0.481
cysD
Sulfate adenylyltransferase subunit 2.
  
  
 0.464
lrp
Leucine-responsive regulatory protein.
   
 
  0.463
cysI_1
Sulfite reductase [NADPH] hemoprotein beta-component.
 
  
 0.461
cysI_2
Sulfite reductase [NADPH] hemoprotein beta-component.
 
  
 0.460
Your Current Organism:
Methylophaga muralis
NCBI taxonomy Id: 291169
Other names: M. muralis, Methylophaga muralis corrig. Doronina et al. 2011, Methylophaga murata, NCIMB 13993, VKM B-2303, strain Kr3
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