STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TUBRATIS_26550Cell cycle protein kinase CDC7 subfamily; Belongs to the protein kinase superfamily. (348 aa)    
Predicted Functional Partners:
TUBRATIS_22190
DNA replication kinase.
   
 0.995
TUBRATIS_13640
DNA replication licensing factor Mcm4; Belongs to the MCM family.
   
 0.994
A0A437AN27
DNA helicase; Belongs to the MCM family.
   
 0.994
TUBRATIS_12480
DNA replication licensing factor Mcm5; Belongs to the MCM family.
   
 0.989
A0A437APQ3
Minichromosome maintenance 3; Belongs to the MCM family.
   
 0.987
A0A437AN50
DNA helicase; Belongs to the MCM family.
   
 0.986
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
    
 0.984
A0A437APT9
Cdc46 Mcm ATPase; Belongs to the MCM family.
   
 0.968
TUBRATIS_18420
Kinase domain-containing protein; Belongs to the PI3/PI4-kinase family.
    
 0.962
TUBRATIS_13830
DNA replication licensing factor Mcm4; Belongs to the MCM family.
   
 0.943
Your Current Organism:
Tubulinosema ratisbonensis
NCBI taxonomy Id: 291195
Other names: T. ratisbonensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.