node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | TUBRATIS_10590 | A0A437AJ91 | A0A437AN73 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Dna replication factor c small subunit. | 0.926 |
FEN1 | TUBRATIS_16630 | A0A437AJ91 | A0A437AKX7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase alpha subunit B. | 0.781 |
FEN1 | TUBRATIS_17650 | A0A437AJ91 | A0A437AKY5 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.996 |
FEN1 | TUBRATIS_19010 | A0A437AJ91 | A0A437AKD6 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Replication factor C. | 0.899 |
FEN1 | TUBRATIS_19310 | A0A437AJ91 | A0A437AKL2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA replication factor C subunit. | 0.903 |
FEN1 | TUBRATIS_20330 | A0A437AJ91 | A0A437AKA6 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Replication factor C large subunit. | 0.509 |
FEN1 | TUBRATIS_21440 | A0A437AJ91 | A0A437AK45 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA replication factor C small subunit. | 0.799 |
FEN1 | TUBRATIS_25060 | A0A437AJ91 | A0A437AIP5 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | BRCT domain-containing protein. | 0.777 |
FEN1 | TUBRATIS_25080 | A0A437AJ91 | A0A437AIP7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA replication factor C small subunit. | 0.730 |
FEN1 | TUBRATIS_29070 | A0A437AJ91 | A0A437AHS9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Replication factor A protein 2. | 0.805 |
TUBRATIS_10590 | FEN1 | A0A437AN73 | A0A437AJ91 | Dna replication factor c small subunit. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.926 |
TUBRATIS_10590 | TUBRATIS_16630 | A0A437AN73 | A0A437AKX7 | Dna replication factor c small subunit. | DNA polymerase alpha subunit B. | 0.920 |
TUBRATIS_10590 | TUBRATIS_17650 | A0A437AN73 | A0A437AKY5 | Dna replication factor c small subunit. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.996 |
TUBRATIS_10590 | TUBRATIS_19010 | A0A437AN73 | A0A437AKD6 | Dna replication factor c small subunit. | Replication factor C. | 0.997 |
TUBRATIS_10590 | TUBRATIS_19310 | A0A437AN73 | A0A437AKL2 | Dna replication factor c small subunit. | DNA replication factor C subunit. | 0.996 |
TUBRATIS_10590 | TUBRATIS_20330 | A0A437AN73 | A0A437AKA6 | Dna replication factor c small subunit. | Replication factor C large subunit. | 0.901 |
TUBRATIS_10590 | TUBRATIS_21440 | A0A437AN73 | A0A437AK45 | Dna replication factor c small subunit. | DNA replication factor C small subunit. | 0.996 |
TUBRATIS_10590 | TUBRATIS_25060 | A0A437AN73 | A0A437AIP5 | Dna replication factor c small subunit. | BRCT domain-containing protein. | 0.992 |
TUBRATIS_10590 | TUBRATIS_25080 | A0A437AN73 | A0A437AIP7 | Dna replication factor c small subunit. | DNA replication factor C small subunit. | 0.977 |
TUBRATIS_10590 | TUBRATIS_29070 | A0A437AN73 | A0A437AHS9 | Dna replication factor c small subunit. | Replication factor A protein 2. | 0.870 |