TUBRATIS_18430 protein (Tubulinosema ratisbonensis)

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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co-expression

protein homology

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Score

TUBRATIS_18430

Tyrosine phosphatase. (241 aa)

Predicted Functional Partners:

A0A437ANL2

0.954

A0A437APA6

0.954

TUBRATIS_24380

0.897

A0A437AQ48

0.892

A0A437APM6

0.862

TUBRATIS_12310

0.854

A0A437ANU6

0.854

TUBRATIS_22550

0.828

TUBRATIS_21970

0.828

TUBRATIS_18210

0.828

Your Current Organism:

Tubulinosema ratisbonensis

NCBI taxonomy Id: 291195
Other names: T. ratisbonensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A437ANL2	A0A437APA6	A0A437ANL2	A0A437APA6	Leucine-rich repeat-containing protein.	Leucine repeat-rich protein.	0.412
A0A437ANL2	A0A437AQ48	A0A437ANL2	A0A437AQ48	Leucine-rich repeat-containing protein.	Chitin deacetylase.	0.973
A0A437ANL2	TUBRATIS_18210	A0A437ANL2	A0A437AKJ1	Leucine-rich repeat-containing protein.	Rho-associated coiled-coil containing kinase.	0.716
A0A437ANL2	TUBRATIS_18430	A0A437ANL2	A0A437AKH6	Leucine-rich repeat-containing protein.	Tyrosine phosphatase.	0.954
A0A437ANL2	TUBRATIS_21970	A0A437ANL2	A0A437AJZ0	Leucine-rich repeat-containing protein.	Myotonic dystrophy kinase like.	0.716
A0A437ANL2	TUBRATIS_22550	A0A437ANL2	A0A437AJN3	Leucine-rich repeat-containing protein.	Rho-associated coiled-coil containing kinase.	0.716
A0A437ANL2	TUBRATIS_24380	A0A437ANL2	A0A437AIX8	Leucine-rich repeat-containing protein.	Exported (PHISTc).	0.425
A0A437ANU6	TUBRATIS_18210	A0A437ANU6	A0A437AKJ1	Serine threonine kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Rho-associated coiled-coil containing kinase.	0.659
A0A437ANU6	TUBRATIS_18430	A0A437ANU6	A0A437AKH6	Serine threonine kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Tyrosine phosphatase.	0.854
A0A437ANU6	TUBRATIS_21970	A0A437ANU6	A0A437AJZ0	Serine threonine kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Myotonic dystrophy kinase like.	0.609
A0A437ANU6	TUBRATIS_22550	A0A437ANU6	A0A437AJN3	Serine threonine kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Rho-associated coiled-coil containing kinase.	0.609
A0A437APA6	A0A437ANL2	A0A437APA6	A0A437ANL2	Leucine repeat-rich protein.	Leucine-rich repeat-containing protein.	0.412
A0A437APA6	A0A437AQ48	A0A437APA6	A0A437AQ48	Leucine repeat-rich protein.	Chitin deacetylase.	0.947
A0A437APA6	TUBRATIS_18210	A0A437APA6	A0A437AKJ1	Leucine repeat-rich protein.	Rho-associated coiled-coil containing kinase.	0.724
A0A437APA6	TUBRATIS_18430	A0A437APA6	A0A437AKH6	Leucine repeat-rich protein.	Tyrosine phosphatase.	0.954
A0A437APA6	TUBRATIS_21970	A0A437APA6	A0A437AJZ0	Leucine repeat-rich protein.	Myotonic dystrophy kinase like.	0.724
A0A437APA6	TUBRATIS_22550	A0A437APA6	A0A437AJN3	Leucine repeat-rich protein.	Rho-associated coiled-coil containing kinase.	0.724
A0A437APM6	TUBRATIS_18430	A0A437APM6	A0A437AKH6	Elongation factor 1 alpha.	Tyrosine phosphatase.	0.862
A0A437AQ48	A0A437ANL2	A0A437AQ48	A0A437ANL2	Chitin deacetylase.	Leucine-rich repeat-containing protein.	0.973
A0A437AQ48	A0A437APA6	A0A437AQ48	A0A437APA6	Chitin deacetylase.	Leucine repeat-rich protein.	0.947

page 1 of 4

Network Stats

number of nodes:

10

number of edges:

23

average node degree:

4.6

avg. local clustering coefficient:

0.815

expected number of edges:

9

PPI enrichment p-value:

8.66e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6148

IBR domain, and Fucose metabolism

2 of 6

2.89

1.56

0.0015

CL:5896

14-3-3 domain, and RAF activation

2 of 5

2.97

1.56

0.0015

CL:3521

LAG1, DNA binding, and Protein of unknown function DUF6699

2 of 5

2.97

1.56

0.0015

CL:5882

Mixed, incl. Protein kinase domain, and Non-membrane spanning protein tyrosine kinase activity

4 of 162

1.76

1.36

0.0015

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03050

Proteasome

2 of 49

1.98

0.79

0.0330

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-109606

Intrinsic Pathway for Apoptosis

2 of 7

2.82

1.24

0.0057

MAP-75035

Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex

2 of 13

2.55

1.23

0.0057

MAP-5625740

RHO GTPases activate PKNs

2 of 10

2.67

1.23

0.0057

MAP-109581

Apoptosis

2 of 23

2.3

1.04

0.0118

MAP-5357801

Programmed Cell Death

2 of 35

2.12

0.9

0.0209

(more ...)

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR040159

Suppressor of hairless-like

2 of 2

3.37

1.39

0.0032

IPR037095

RBP-J/Cbf11, DNA binding domain superfamily

2 of 2

3.37

1.39

0.0032

IPR036815

14-3-3 domain superfamily

2 of 2

3.37

1.39

0.0032

IPR036358

Beta-trefoil domain superfamily

2 of 2

3.37

1.39

0.0032

IPR023410

14-3-3 domain

2 of 2

3.37

1.39

0.0032

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01268

Beta-trefoil DNA-binding domain

2 of 2

3.37

1.93

0.00034

SM01267

LAG1, DNA binding

2 of 2

3.37

1.93

0.00034

SM00101

14-3-3 homologues

2 of 2

3.37

1.93

0.00034

SM00248

Ankyrin repeats

2 of 67

1.84

0.77

0.0327

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