| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ffh | rmpH | BPEN_178 | BPEN_014 | 4.5S-RNP protein; GTP-binding export factor; part of signal recognition particle with 4.5 RNA; ortholog to Escherichia coli bnum: b2610; MultiFun: Transport 4.3.A.5; Transport 4.S.160. | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | 0.825 |
| ffh | rplB | BPEN_178 | BPEN_201 | 4.5S-RNP protein; GTP-binding export factor; part of signal recognition particle with 4.5 RNA; ortholog to Escherichia coli bnum: b2610; MultiFun: Transport 4.3.A.5; Transport 4.S.160. | 50S ribosomal subunit protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.856 |
| ffh | rplD | BPEN_178 | BPEN_199 | 4.5S-RNP protein; GTP-binding export factor; part of signal recognition particle with 4.5 RNA; ortholog to Escherichia coli bnum: b2610; MultiFun: Transport 4.3.A.5; Transport 4.S.160. | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.863 |
| ffh | secE | BPEN_178 | BPEN_583 | 4.5S-RNP protein; GTP-binding export factor; part of signal recognition particle with 4.5 RNA; ortholog to Escherichia coli bnum: b2610; MultiFun: Transport 4.3.A.5; Transport 4.S.160. | Preprotein translocase, membrane component; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.956 |
| ffh | secG | BPEN_178 | BPEN_104 | 4.5S-RNP protein; GTP-binding export factor; part of signal recognition particle with 4.5 RNA; ortholog to Escherichia coli bnum: b2610; MultiFun: Transport 4.3.A.5; Transport 4.S.160. | Preprotein translocase, membrane component; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.951 |
| ffh | secY | BPEN_178 | BPEN_218 | 4.5S-RNP protein; GTP-binding export factor; part of signal recognition particle with 4.5 RNA; ortholog to Escherichia coli bnum: b2610; MultiFun: Transport 4.3.A.5; Transport 4.S.160. | Preprotein translocase, membrane component; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.965 |
| ffh | yidCD | BPEN_178 | BPEN_012 | 4.5S-RNP protein; GTP-binding export factor; part of signal recognition particle with 4.5 RNA; ortholog to Escherichia coli bnum: b2610; MultiFun: Transport 4.3.A.5; Transport 4.S.160. | Putative protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily. | 0.938 |
| rho | rnpA | BPEN_607 | BPEN_013 | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | RNase P, protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.730 |
| rho | rplB | BPEN_607 | BPEN_201 | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 50S ribosomal subunit protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.462 |
| rho | rplD | BPEN_607 | BPEN_199 | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.443 |
| rho | yidCD | BPEN_607 | BPEN_012 | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | Putative protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily. | 0.981 |
| rmpH | ffh | BPEN_014 | BPEN_178 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | 4.5S-RNP protein; GTP-binding export factor; part of signal recognition particle with 4.5 RNA; ortholog to Escherichia coli bnum: b2610; MultiFun: Transport 4.3.A.5; Transport 4.S.160. | 0.825 |
| rmpH | rnpA | BPEN_014 | BPEN_013 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | RNase P, protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.994 |
| rmpH | rplB | BPEN_014 | BPEN_201 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | 50S ribosomal subunit protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.934 |
| rmpH | rplD | BPEN_014 | BPEN_199 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.957 |
| rmpH | secE | BPEN_014 | BPEN_583 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | Preprotein translocase, membrane component; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.721 |
| rmpH | secG | BPEN_014 | BPEN_104 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | Preprotein translocase, membrane component; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.737 |
| rmpH | secY | BPEN_014 | BPEN_218 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | Preprotein translocase, membrane component; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.605 |
| rmpH | trmE | BPEN_014 | BPEN_011 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | GTPase for tRNA modification and thiophene and furan oxidation; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.846 |
| rmpH | yidCD | BPEN_014 | BPEN_012 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | Putative protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily. | 0.995 |
