| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dnaN | rmpH | BPEN_015 | BPEN_014 | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | 0.762 |
| dnaN | rnpA | BPEN_015 | BPEN_013 | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RNase P, protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.791 |
| dnaN | trmE | BPEN_015 | BPEN_011 | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | GTPase for tRNA modification and thiophene and furan oxidation; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.606 |
| dnaN | yidCD | BPEN_015 | BPEN_012 | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily. | 0.745 |
| rmpH | dnaN | BPEN_014 | BPEN_015 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.762 |
| rmpH | rnpA | BPEN_014 | BPEN_013 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | RNase P, protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.994 |
| rmpH | rplD | BPEN_014 | BPEN_199 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.957 |
| rmpH | rpmB | BPEN_014 | BPEN_636 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | 50S ribosomal subunit protein L28; Ortholog to Escherichia coli bnum: b3637; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL28 family. | 0.990 |
| rmpH | rpsJ | BPEN_014 | BPEN_197 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | 30S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.974 |
| rmpH | rpsL | BPEN_014 | BPEN_587 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | 30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.981 |
| rmpH | rpsP | BPEN_014 | BPEN_179 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | 30S ribosomal subunit protein S16; Ortholog to Escherichia coli bnum: b2609; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bS16 family. | 0.979 |
| rmpH | rpsT | BPEN_014 | BPEN_120 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | 30S ribosomal subunit protein S20; Binds directly to 16S ribosomal RNA. | 0.987 |
| rmpH | trmE | BPEN_014 | BPEN_011 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | GTPase for tRNA modification and thiophene and furan oxidation; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.846 |
| rmpH | yidCD | BPEN_014 | BPEN_012 | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | Putative protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily. | 0.995 |
| rnpA | dnaN | BPEN_013 | BPEN_015 | RNase P, protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.791 |
| rnpA | rmpH | BPEN_013 | BPEN_014 | RNase P, protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 50S ribosomal subunit protein L34; Ortholog to Escherichia coli bnum: b3703; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL34 family. | 0.994 |
| rnpA | rplD | BPEN_013 | BPEN_199 | RNase P, protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.792 |
| rnpA | rpmB | BPEN_013 | BPEN_636 | RNase P, protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 50S ribosomal subunit protein L28; Ortholog to Escherichia coli bnum: b3637; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the bacterial ribosomal protein bL28 family. | 0.847 |
| rnpA | rpsJ | BPEN_013 | BPEN_197 | RNase P, protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 30S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.844 |
| rnpA | rpsL | BPEN_013 | BPEN_587 | RNase P, protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.805 |
