Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ytfMPutative outer membrane protein; Ortholog to E. coli bnum: b4220; in-frame premature UAG termination codon is located within the ytfM sequence, and a -1 frameshift would be required for synthesis of ytfM; RNA polymerase or ribosomal slippage; possible young pseudogene; MultiFun: Cell structure 6.1. (587 aa)    
Predicted Functional Partners:
ytfN
Putative exported protein; Ortholog to Escherichia coli bnum: b4221.
 
 
 0.997
lolB
Outer membrane lipoprotein precursor; Ortholog to Escherichia coli bnum: b1209; MultiFun: Cell structure 6.1.
  
     0.712
hns
DNA-binding protein HLP-II (HU, BH2, HD, NS); Ortholog to Escherichia coli bnum: b1237; MultiFun: Cell processes 5.3; Cell structure 6.4; Information transfer 2.2.2, 2.3.7; Regulation 3.1.2; Belongs to the histone-like protein H-NS family.
  
     0.711
dsbA
Periplasmic protein disulfide isomerase I, disulfide bond formation; Ortholog to Escherichia coli bnum: b3860; MultiFun: Cell processes 5.5; Information transfer 2.3.4.
  
     0.575
yciC
Putative membrane protein, transport; Ortholog to Escherichia coli bnum: b1255; MultiFun: Cell structure 6.1.
  
     0.556
ybiS
Putative exported protein; Ortholog to E. coli bnum: b0819; in-frame premature UAG termination codon is located within the ybiS sequence, and a +1 frameshift would be required for synthesis of ybiS; RNA polymerase or ribosomal slippage; possible young pseudogene.
  
   
 0.532
rpmC
50S ribosomal subunit protein L29; Ortholog to Escherichia coli bnum: b3312; MultiFun: Cell structure 6.6; Information transfer 2.3.2, 2.3.8; Belongs to the universal ribosomal protein uL29 family.
  
     0.526
yrbK
Possible exported protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.
  
     0.503
yjgP
Putative transmembrane protein, transport; Ortholog to Escherichia coli bnum: b4261; MultiFun: Cell structure 6.1; Transport 4.
  
     0.498
yjeP
Putative membrane protein; Ortholog to Escherichia coli bnum: b4159; MultiFun: Transport 4.9.B.
  
    0.493
Your Current Organism:
Blochmannia pennsylvanicus
NCBI taxonomy Id: 291272
Other names: C. Blochmannia pennsylvanicus str. BPEN, Candidatus Blochmannia pennsylvanicus BPEN, Candidatus Blochmannia pennsylvanicus str. BPEN, Candidatus Blochmannia pennsylvanicus strain BPEN
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