| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cyoA | cyoB | BPEN_252 | BPEN_251 | Cytochrome o ubiquinol oxidase, subunit II; Ortholog to Escherichia coli bnum: b0432; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82. | Cytochrome o ubiquinol oxidase, subunit I; Ortholog to Escherichia coli bnum: b0431; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82; Belongs to the heme-copper respiratory oxidase family. | 0.999 |
| cyoA | cyoC | BPEN_252 | BPEN_250 | Cytochrome o ubiquinol oxidase, subunit II; Ortholog to Escherichia coli bnum: b0432; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82. | Cytochrome o ubiquinol oxidase, subunit III; Ortholog to Escherichia coli bnum: b0430; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82. | 0.999 |
| cyoA | cyoD | BPEN_252 | BPEN_249 | Cytochrome o ubiquinol oxidase, subunit II; Ortholog to Escherichia coli bnum: b0432; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82. | Cytochrome o ubiquinol oxidase, subunit IV; Ortholog to Escherichia coli bnum: b0429; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2. | 0.999 |
| cyoA | cyoE | BPEN_252 | BPEN_248 | Cytochrome o ubiquinol oxidase, subunit II; Ortholog to Escherichia coli bnum: b0432; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82. | Protohaeme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | 0.997 |
| cyoA | sdhC | BPEN_252 | BPEN_337 | Cytochrome o ubiquinol oxidase, subunit II; Ortholog to Escherichia coli bnum: b0432; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82. | Succinate dehydrogenase cytochrome b-556 subunit; Ortholog to Escherichia coli bnum: b0721; MultiFun: Cell structure 6.1; Metabolism 1.3.4, 1.3.6, 1.4.1, 1.4.3, 1.6.15.1. | 0.843 |
| cyoA | yajR | BPEN_252 | BPEN_247 | Cytochrome o ubiquinol oxidase, subunit II; Ortholog to Escherichia coli bnum: b0432; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82. | Putative transport protein (MFS family); Ortholog to Escherichia coli bnum: b0427; MultiFun: Cell processes 5.6.4; Cell structure 6.1; Transport 4.2.A.1,4.S.49. | 0.407 |
| cyoB | cyoA | BPEN_251 | BPEN_252 | Cytochrome o ubiquinol oxidase, subunit I; Ortholog to Escherichia coli bnum: b0431; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82; Belongs to the heme-copper respiratory oxidase family. | Cytochrome o ubiquinol oxidase, subunit II; Ortholog to Escherichia coli bnum: b0432; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82. | 0.999 |
| cyoB | cyoC | BPEN_251 | BPEN_250 | Cytochrome o ubiquinol oxidase, subunit I; Ortholog to Escherichia coli bnum: b0431; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82; Belongs to the heme-copper respiratory oxidase family. | Cytochrome o ubiquinol oxidase, subunit III; Ortholog to Escherichia coli bnum: b0430; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82. | 0.999 |
| cyoB | cyoD | BPEN_251 | BPEN_249 | Cytochrome o ubiquinol oxidase, subunit I; Ortholog to Escherichia coli bnum: b0431; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82; Belongs to the heme-copper respiratory oxidase family. | Cytochrome o ubiquinol oxidase, subunit IV; Ortholog to Escherichia coli bnum: b0429; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2. | 0.999 |
| cyoB | cyoE | BPEN_251 | BPEN_248 | Cytochrome o ubiquinol oxidase, subunit I; Ortholog to Escherichia coli bnum: b0431; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82; Belongs to the heme-copper respiratory oxidase family. | Protohaeme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | 0.999 |
| cyoB | sdhC | BPEN_251 | BPEN_337 | Cytochrome o ubiquinol oxidase, subunit I; Ortholog to Escherichia coli bnum: b0431; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82; Belongs to the heme-copper respiratory oxidase family. | Succinate dehydrogenase cytochrome b-556 subunit; Ortholog to Escherichia coli bnum: b0721; MultiFun: Cell structure 6.1; Metabolism 1.3.4, 1.3.6, 1.4.1, 1.4.3, 1.6.15.1. | 0.728 |
| cyoB | yajR | BPEN_251 | BPEN_247 | Cytochrome o ubiquinol oxidase, subunit I; Ortholog to Escherichia coli bnum: b0431; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82; Belongs to the heme-copper respiratory oxidase family. | Putative transport protein (MFS family); Ortholog to Escherichia coli bnum: b0427; MultiFun: Cell processes 5.6.4; Cell structure 6.1; Transport 4.2.A.1,4.S.49. | 0.482 |
| cyoC | cyoA | BPEN_250 | BPEN_252 | Cytochrome o ubiquinol oxidase, subunit III; Ortholog to Escherichia coli bnum: b0430; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82. | Cytochrome o ubiquinol oxidase, subunit II; Ortholog to Escherichia coli bnum: b0432; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82. | 0.999 |
| cyoC | cyoB | BPEN_250 | BPEN_251 | Cytochrome o ubiquinol oxidase, subunit III; Ortholog to Escherichia coli bnum: b0430; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82. | Cytochrome o ubiquinol oxidase, subunit I; Ortholog to Escherichia coli bnum: b0431; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82; Belongs to the heme-copper respiratory oxidase family. | 0.999 |
| cyoC | cyoD | BPEN_250 | BPEN_249 | Cytochrome o ubiquinol oxidase, subunit III; Ortholog to Escherichia coli bnum: b0430; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82. | Cytochrome o ubiquinol oxidase, subunit IV; Ortholog to Escherichia coli bnum: b0429; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2. | 0.999 |
| cyoC | cyoE | BPEN_250 | BPEN_248 | Cytochrome o ubiquinol oxidase, subunit III; Ortholog to Escherichia coli bnum: b0430; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82. | Protohaeme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | 0.999 |
| cyoC | sdhC | BPEN_250 | BPEN_337 | Cytochrome o ubiquinol oxidase, subunit III; Ortholog to Escherichia coli bnum: b0430; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82. | Succinate dehydrogenase cytochrome b-556 subunit; Ortholog to Escherichia coli bnum: b0721; MultiFun: Cell structure 6.1; Metabolism 1.3.4, 1.3.6, 1.4.1, 1.4.3, 1.6.15.1. | 0.653 |
| cyoC | yajR | BPEN_250 | BPEN_247 | Cytochrome o ubiquinol oxidase, subunit III; Ortholog to Escherichia coli bnum: b0430; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82. | Putative transport protein (MFS family); Ortholog to Escherichia coli bnum: b0427; MultiFun: Cell processes 5.6.4; Cell structure 6.1; Transport 4.2.A.1,4.S.49. | 0.482 |
| cyoD | cyoA | BPEN_249 | BPEN_252 | Cytochrome o ubiquinol oxidase, subunit IV; Ortholog to Escherichia coli bnum: b0429; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2. | Cytochrome o ubiquinol oxidase, subunit II; Ortholog to Escherichia coli bnum: b0432; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82. | 0.999 |
| cyoD | cyoB | BPEN_249 | BPEN_251 | Cytochrome o ubiquinol oxidase, subunit IV; Ortholog to Escherichia coli bnum: b0429; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2. | Cytochrome o ubiquinol oxidase, subunit I; Ortholog to Escherichia coli bnum: b0431; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82; Belongs to the heme-copper respiratory oxidase family. | 0.999 |