| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| holA | holD | BPEN_319 | BPEN_114 | DNA polymerase III, delta subunit; Ortholog to Escherichia coli bnum: b0640; MultiFun: Information transfer 2.1.1. | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | 0.996 |
| holA | imp | BPEN_319 | BPEN_133 | DNA polymerase III, delta subunit; Ortholog to Escherichia coli bnum: b0640; MultiFun: Information transfer 2.1.1. | Organic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.703 |
| holA | leuS | BPEN_319 | BPEN_321 | DNA polymerase III, delta subunit; Ortholog to Escherichia coli bnum: b0640; MultiFun: Information transfer 2.1.1. | leucyl-tRNA synthetase; Ortholog to Escherichia coli bnum: b0642; MultiFun: Information transfer 2.3.1; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.616 |
| holA | omp | BPEN_319 | BPEN_491 | DNA polymerase III, delta subunit; Ortholog to Escherichia coli bnum: b0640; MultiFun: Information transfer 2.1.1. | Outer membrane protein; Ortholog to Escherichia coli bnum: b2215; MultiFun: Cell structure 6.1; Transport 4.1.B.1, 4.S.92. | 0.453 |
| holA | rlpB | BPEN_319 | BPEN_320 | DNA polymerase III, delta subunit; Ortholog to Escherichia coli bnum: b0640; MultiFun: Information transfer 2.1.1. | Rare lipoprotein B precursor; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.804 |
| holA | ycfM | BPEN_319 | BPEN_409 | DNA polymerase III, delta subunit; Ortholog to Escherichia coli bnum: b0640; MultiFun: Information transfer 2.1.1. | Putative fibronectin-binding protein; Ortholog to Escherichia coli bnum: b1105. | 0.499 |
| holA | yeeX | BPEN_319 | BPEN_475 | DNA polymerase III, delta subunit; Ortholog to Escherichia coli bnum: b0640; MultiFun: Information transfer 2.1.1. | Conserved hypothetical protein; Ortholog to Escherichia coli bnum: b2007; Belongs to the UPF0265 family. | 0.520 |
| holA | yhcB | BPEN_319 | BPEN_049 | DNA polymerase III, delta subunit; Ortholog to Escherichia coli bnum: b0640; MultiFun: Information transfer 2.1.1. | Conserved hypothetical protein; Ortholog to Escherichia coli bnum: b3233. | 0.410 |
| holD | holA | BPEN_114 | BPEN_319 | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | DNA polymerase III, delta subunit; Ortholog to Escherichia coli bnum: b0640; MultiFun: Information transfer 2.1.1. | 0.996 |
| holD | imp | BPEN_114 | BPEN_133 | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | Organic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.660 |
| holD | lolB | BPEN_114 | BPEN_358 | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | Outer membrane lipoprotein precursor; Ortholog to Escherichia coli bnum: b1209; MultiFun: Cell structure 6.1. | 0.696 |
| holD | omp | BPEN_114 | BPEN_491 | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | Outer membrane protein; Ortholog to Escherichia coli bnum: b2215; MultiFun: Cell structure 6.1; Transport 4.1.B.1, 4.S.92. | 0.774 |
| holD | rlpB | BPEN_114 | BPEN_320 | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | Rare lipoprotein B precursor; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.773 |
| holD | ycfM | BPEN_114 | BPEN_409 | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | Putative fibronectin-binding protein; Ortholog to Escherichia coli bnum: b1105. | 0.770 |
| holD | yeeX | BPEN_114 | BPEN_475 | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | Conserved hypothetical protein; Ortholog to Escherichia coli bnum: b2007; Belongs to the UPF0265 family. | 0.741 |
| holD | yhcB | BPEN_114 | BPEN_049 | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | Conserved hypothetical protein; Ortholog to Escherichia coli bnum: b3233. | 0.774 |
| holD | yrbK | BPEN_114 | BPEN_045 | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | Possible exported protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.606 |
| imp | holA | BPEN_133 | BPEN_319 | Organic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | DNA polymerase III, delta subunit; Ortholog to Escherichia coli bnum: b0640; MultiFun: Information transfer 2.1.1. | 0.703 |
| imp | holD | BPEN_133 | BPEN_114 | Organic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | 0.660 |
| imp | lolB | BPEN_133 | BPEN_358 | Organic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | Outer membrane lipoprotein precursor; Ortholog to Escherichia coli bnum: b1209; MultiFun: Cell structure 6.1. | 0.559 |