Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ycfMPutative fibronectin-binding protein; Ortholog to Escherichia coli bnum: b1105. (178 aa)    
Predicted Functional Partners:
mrcB
Penicillin-binding protein 1b: glycosyl transferase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
  
 
 
 0.901
omp
Outer membrane protein; Ortholog to Escherichia coli bnum: b2215; MultiFun: Cell structure 6.1; Transport 4.1.B.1, 4.S.92.
  
     0.773
holD
DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
     0.770
lpp
Murein lipoprotein; Ortholog to Escherichia coli bnum: b1677; MultiFun: Cell structure 6.1, 6.2; Metabolism 1.6.7.
  
     0.770
yccV
Conserved hypothetical protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family.
  
     0.766
yhcB
Conserved hypothetical protein; Ortholog to Escherichia coli bnum: b3233.
  
     0.765
holB
DNA polymerase III, delta prime subunit; Ortholog to Escherichia coli bnum: b1099; MultiFun: Information transfer 2.1.1.
 
     0.765
rlpB
Rare lipoprotein B precursor; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.
  
     0.756
tolA
TolA; Required for outer membrane integrity, uptake of group A colicins, role in translocation of filamenous phage DNA to cytoplasm, role in surface expression of O-antigen; ortholog to Escherichia coli bnum: b0739; MultiFun: Cell structure 6.1; Metabolism 1.6.3.1.
  
     0.756
yciC
Putative membrane protein, transport; Ortholog to Escherichia coli bnum: b1255; MultiFun: Cell structure 6.1.
  
     0.725
Your Current Organism:
Blochmannia pennsylvanicus
NCBI taxonomy Id: 291272
Other names: C. Blochmannia pennsylvanicus str. BPEN, Candidatus Blochmannia pennsylvanicus BPEN, Candidatus Blochmannia pennsylvanicus str. BPEN, Candidatus Blochmannia pennsylvanicus strain BPEN
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