Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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tonBEnergy transducer; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (242 aa)    
Predicted Functional Partners:
tolR
TolR; Role in outer membrane integrity, uptake of group A colicins (TonB-independent), and phage DNA; ortholog to Escherichia coli bnum: b0738; MultiFun: Cell structure 6.1.
 
 
 0.986
tolQ
TolQ; Inner membrane protein required for outer membrane integrity, uptake of group A colicins and phage DNA; ortholog to Escherichia coli bnum: b0737; MultiFun: Cell structure 6.1.
  
 
 0.965
oprC
OprC; Outer membrane protein.
  
 
 0.952
lpp
Murein lipoprotein; Ortholog to Escherichia coli bnum: b1677; MultiFun: Cell structure 6.1, 6.2; Metabolism 1.6.7.
  
 
   0.943
tolB
TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
 
 
 0.892
omp
Outer membrane protein; Ortholog to Escherichia coli bnum: b2215; MultiFun: Cell structure 6.1; Transport 4.1.B.1, 4.S.92.
  
   
 0.698
rpoB
DNA-directed RNA polymerase, beta-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.538
ycfM
Putative fibronectin-binding protein; Ortholog to Escherichia coli bnum: b1105.
  
     0.520
holD
DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
     0.490
infB
Translation initiation factor IF2-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
      
 0.487
Your Current Organism:
Blochmannia pennsylvanicus
NCBI taxonomy Id: 291272
Other names: C. Blochmannia pennsylvanicus str. BPEN, Candidatus Blochmannia pennsylvanicus BPEN, Candidatus Blochmannia pennsylvanicus str. BPEN, Candidatus Blochmannia pennsylvanicus strain BPEN
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