Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
manXPTS family enzyme IIA/enzyme IIB, mannose-specific; Ortholog to Escherichia coli bnum: b1817; MultiFun: Metabolism 1.1.1; Transport 4.4.A.6, 4.S.116. (327 aa)    
Predicted Functional Partners:
manY
PTS family enzyme IIC, mannose-specific; Ortholog to Escherichia coli bnum: b1818; MultiFun: Cell structure 6.1; Metabolism 1.1.1; Transport 4.4.A.6, 4.S.116.
 
 0.999
manZ
PTS family enzyme IID, mannose-specific; Ortholog to Escherichia coli bnum: b1819; MultiFun: Cell structure 6.1; Metabolism 1.1.1; Transport 4.4.A.6, 4.S.116.
 
 0.999
ptsH
PTS family Hpr protein, phosphohistidinoprotein-hexose phosphotransferase; Ortholog to Escherichia coli bnum: b2415; MultiFun: Metabolism 1.1.1; Transport 4.8.A.8, 4.S.173.
   
 0.997
ptsI
PTS family enzyme I and Hpr components, PEP-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
  
  
 0.755
nagB
Glucosamine-6-phosphate isomerase; Ortholog to Escherichia coli bnum: b0678; MultiFun: Metabolism 1.7.12.
  
  
 0.724
fabG
3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.600
nagA
N-acetylglucosamine-6-phosphate deacetylase; Ortholog to Escherichia coli bnum: b0677; MultiFun: Metabolism 1.7.12.
     
 0.570
fbaA
Fructose 1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
  
 0.509
ribD
Pyrimidine deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
       0.434
gutQ
Putative phosphosugar binding protein; Ortholog to Escherichia coli bnum: b2708; MultiFun: Cell structure 6.7; Regulation 3.1.4.
       0.434
Your Current Organism:
Blochmannia pennsylvanicus
NCBI taxonomy Id: 291272
Other names: C. Blochmannia pennsylvanicus str. BPEN, Candidatus Blochmannia pennsylvanicus BPEN, Candidatus Blochmannia pennsylvanicus str. BPEN, Candidatus Blochmannia pennsylvanicus strain BPEN
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.