Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mqoProbable malate:quinone oxidoreductase; Ortholog to Escherichia coli bnum: b2210; MultiFun: Metabolism 1.3.4; malate dehydrogenase. (515 aa)    
Predicted Functional Partners:
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
    
 0.926
purB
Adenylosuccinate lyase; Ortholog to Escherichia coli bnum: b1131; MultiFun: Metabolism 1.5.2.1; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
  0.800
aspC
Aspartate aminotransferase; Ortholog to Escherichia coli bnum: b0928; MultiFun: Metabolism 1.1.3, 1.5.1.5.
     
  0.800
cyoA
Cytochrome o ubiquinol oxidase, subunit II; Ortholog to Escherichia coli bnum: b0432; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82.
   
 
 0.505
cyoC
Cytochrome o ubiquinol oxidase, subunit III; Ortholog to Escherichia coli bnum: b0430; MultiFun: Cell structure 6.1; Metabolism 1.3.6, 1.4.2; Transport 4.3.D.4, 4.S.82.
    
   0.474
cysG
Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
       0.422
Your Current Organism:
Blochmannia pennsylvanicus
NCBI taxonomy Id: 291272
Other names: C. Blochmannia pennsylvanicus str. BPEN, Candidatus Blochmannia pennsylvanicus BPEN, Candidatus Blochmannia pennsylvanicus str. BPEN, Candidatus Blochmannia pennsylvanicus strain BPEN
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