| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DnaA | dnaA | XOO1300 | XOO0001 | ATPase involved in DNA replication initiation; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the DnaA family. HdA subfamily. | Chromosomal replication initiator; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.674 |
| DnaA | dnaN | XOO1300 | XOO0002 | ATPase involved in DNA replication initiation; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the DnaA family. HdA subfamily. | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.990 |
| DnaA | polA | XOO1300 | XOO4240 | ATPase involved in DNA replication initiation; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the DnaA family. HdA subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.431 |
| dnaA | DnaA | XOO0001 | XOO1300 | Chromosomal replication initiator; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | ATPase involved in DNA replication initiation; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the DnaA family. HdA subfamily. | 0.674 |
| dnaA | dnaE1 | XOO0001 | XOO1962 | Chromosomal replication initiator; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA polymerase III alpha chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.537 |
| dnaA | dnaN | XOO0001 | XOO0002 | Chromosomal replication initiator; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.995 |
| dnaA | dnaX | XOO0001 | XOO1064 | Chromosomal replication initiator; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA polymerase III tau and gamma subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.486 |
| dnaA | polA | XOO0001 | XOO4240 | Chromosomal replication initiator; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.511 |
| dnaE1 | dnaA | XOO1962 | XOO0001 | DNA polymerase III alpha chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Chromosomal replication initiator; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.537 |
| dnaE1 | dnaN | XOO1962 | XOO0002 | DNA polymerase III alpha chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.987 |
| dnaE1 | dnaQ | XOO1962 | XOO1042 | DNA polymerase III alpha chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | DNA polymerase III epsilon chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.981 |
| dnaE1 | dnaX | XOO1962 | XOO1064 | DNA polymerase III alpha chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | DNA polymerase III tau and gamma subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.986 |
| dnaE1 | holA | XOO1962 | XOO3327 | DNA polymerase III alpha chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | DNA polymerase III delta subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.983 |
| dnaE1 | holB | XOO1962 | XOO0886 | DNA polymerase III alpha chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | DNA polymerase III delta' subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.981 |
| dnaE1 | polA | XOO1962 | XOO4240 | DNA polymerase III alpha chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.636 |
| dnaN | DnaA | XOO0002 | XOO1300 | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | ATPase involved in DNA replication initiation; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the DnaA family. HdA subfamily. | 0.990 |
| dnaN | dnaA | XOO0002 | XOO0001 | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | Chromosomal replication initiator; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.995 |
| dnaN | dnaE1 | XOO0002 | XOO1962 | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | DNA polymerase III alpha chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.987 |
| dnaN | dnaQ | XOO0002 | XOO1042 | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | DNA polymerase III epsilon chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.991 |
| dnaN | dnaX | XOO0002 | XOO1064 | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | DNA polymerase III tau and gamma subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.993 |