| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XOO0175 | dnaN | XOO0175 | XOO0002 | Topoisomerase IB; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.667 |
| XOO0175 | glgA | XOO0175 | XOO0112 | Topoisomerase IB; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. | 0.660 |
| XOO0175 | gyrB | XOO0175 | XOO0004 | Topoisomerase IB; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.732 |
| XOO0175 | lig2 | XOO0175 | XOO1875 | Topoisomerase IB; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | DNA ligase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.701 |
| XOO0175 | parE | XOO0175 | XOO2969 | Topoisomerase IB; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.732 |
| XOO0175 | recQ | XOO0175 | XOO1723 | Topoisomerase IB; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | DNA helicase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.767 |
| XOO0175 | rnhB | XOO0175 | XOO1963 | Topoisomerase IB; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.770 |
| XOO0175 | xrvA | XOO0175 | XOO2744 | Topoisomerase IB; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Virulence regulator; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.601 |
| XOO0175 | xrvA-2 | XOO0175 | XOO3363 | Topoisomerase IB; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Virulence regulator; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.603 |
| XOO0175 | ybdR | XOO0175 | XOO0635 | Topoisomerase IB; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Zn-dependent alcohol dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.659 |
| dnaN | XOO0175 | XOO0002 | XOO0175 | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | Topoisomerase IB; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.667 |
| dnaN | gyrB | XOO0002 | XOO0004 | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.891 |
| dnaN | lig2 | XOO0002 | XOO1875 | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | DNA ligase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.918 |
| dnaN | parE | XOO0002 | XOO2969 | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | Topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.584 |
| dnaN | recQ | XOO0002 | XOO1723 | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | DNA helicase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.788 |
| dnaN | rnhB | XOO0002 | XOO1963 | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.852 |
| glgA | XOO0175 | XOO0112 | XOO0175 | Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. | Topoisomerase IB; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.660 |
| gyrB | XOO0175 | XOO0004 | XOO0175 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Topoisomerase IB; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.732 |
| gyrB | dnaN | XOO0004 | XOO0002 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA polymerase III beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.891 |
| gyrB | recQ | XOO0004 | XOO1723 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA helicase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.586 |