| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PrsA | purF | XOO3603 | XOO3675 | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.941 |
| PrsA | purL | XOO3603 | XOO0841 | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | Phosphoribosylformylglycinamidine synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.776 |
| PrsA | pyrB | XOO3603 | XOO1427 | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | Aspartate carbamoyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.626 |
| PrsA | pyrE | XOO3603 | XOO0508 | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | Orotate phosphoribosyl transferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.876 |
| PrsA | pyrF | XOO3603 | XOO0247 | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.406 |
| carA | carB | XOO2888 | XOO2887 | Carbamoyl-phosphate synthase small chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CarA family. | Carbamoyl-phosphate synthase large chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CarB family. | 0.999 |
| carA | purF | XOO2888 | XOO3675 | Carbamoyl-phosphate synthase small chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CarA family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.967 |
| carA | purL | XOO2888 | XOO0841 | Carbamoyl-phosphate synthase small chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CarA family. | Phosphoribosylformylglycinamidine synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.965 |
| carA | pyrB | XOO2888 | XOO1427 | Carbamoyl-phosphate synthase small chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CarA family. | Aspartate carbamoyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carA | pyrC | XOO2888 | XOO2683 | Carbamoyl-phosphate synthase small chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CarA family. | Dihydroorotase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.996 |
| carA | pyrD | XOO2888 | XOO2237 | Carbamoyl-phosphate synthase small chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.968 |
| carA | pyrE | XOO2888 | XOO0508 | Carbamoyl-phosphate synthase small chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CarA family. | Orotate phosphoribosyl transferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.943 |
| carA | pyrF | XOO2888 | XOO0247 | Carbamoyl-phosphate synthase small chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CarA family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.943 |
| carB | carA | XOO2887 | XOO2888 | Carbamoyl-phosphate synthase large chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CarB family. | Carbamoyl-phosphate synthase small chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CarA family. | 0.999 |
| carB | purF | XOO2887 | XOO3675 | Carbamoyl-phosphate synthase large chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CarB family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.980 |
| carB | purL | XOO2887 | XOO0841 | Carbamoyl-phosphate synthase large chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CarB family. | Phosphoribosylformylglycinamidine synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.684 |
| carB | pyrB | XOO2887 | XOO1427 | Carbamoyl-phosphate synthase large chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CarB family. | Aspartate carbamoyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carB | pyrC | XOO2887 | XOO2683 | Carbamoyl-phosphate synthase large chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CarB family. | Dihydroorotase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.996 |
| carB | pyrD | XOO2887 | XOO2237 | Carbamoyl-phosphate synthase large chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CarB family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.972 |
| carB | pyrE | XOO2887 | XOO0508 | Carbamoyl-phosphate synthase large chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CarB family. | Orotate phosphoribosyl transferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.957 |