| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AmpD | ampG | XOO2445 | XOO0510 | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Signal transducer; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.694 |
| AmpD | anmK | XOO2445 | XOO0512 | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.796 |
| AmpD | nagZ | XOO2445 | XOO1867 | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | N-acetyl-beta-glucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.796 |
| AmpD-2 | ampG | XOO4100 | XOO0510 | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Signal transducer; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.828 |
| AmpD-2 | anmK | XOO4100 | XOO0512 | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.898 |
| AmpD-2 | mpl | XOO4100 | XOO0964 | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | UDP-N-acetylmuramate-L-alanine ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.525 |
| AmpD-2 | nagZ | XOO4100 | XOO1867 | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | N-acetyl-beta-glucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.884 |
| XOO0511 | ampG | XOO0511 | XOO0510 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Signal transducer; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.649 |
| XOO0511 | exoA | XOO0511 | XOO0509 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Exodeoxyribonuclease III; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.415 |
| ampG | AmpD | XOO0510 | XOO2445 | Signal transducer; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.694 |
| ampG | AmpD-2 | XOO0510 | XOO4100 | Signal transducer; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.828 |
| ampG | XOO0511 | XOO0510 | XOO0511 | Signal transducer; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.649 |
| ampG | anmK | XOO0510 | XOO0512 | Signal transducer; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.803 |
| ampG | cebR | XOO0510 | XOO1101 | Signal transducer; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Transcriptional regulator; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.480 |
| ampG | exoA | XOO0510 | XOO0509 | Signal transducer; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Exodeoxyribonuclease III; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.598 |
| ampG | mpl | XOO0510 | XOO0964 | Signal transducer; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | UDP-N-acetylmuramate-L-alanine ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.427 |
| ampG | nagZ | XOO0510 | XOO1867 | Signal transducer; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | N-acetyl-beta-glucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.864 |
| ampG | pyrE | XOO0510 | XOO0508 | Signal transducer; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Orotate phosphoribosyl transferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.527 |
| ampG | ttgF | XOO0510 | XOO1560 | Signal transducer; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Outer membrane channel protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.425 |
| anmK | AmpD | XOO0512 | XOO2445 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Negative regulator of beta-lactamase expression; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.796 |