| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NlpD | amiC-2 | XOO0513 | XOO2733 | Membrane proteins related to metalloendopeptidases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | N-acetylmuramoyl-L-alanine amidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.431 |
| NlpD | anmK | XOO0513 | XOO0512 | Membrane proteins related to metalloendopeptidases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.744 |
| NlpD | dniR-2 | XOO0513 | XOO3266 | Membrane proteins related to metalloendopeptidases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Membrane-bound lytic murein transglycosylase D precursor; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.422 |
| NlpD | dxr | XOO0513 | XOO1970 | Membrane proteins related to metalloendopeptidases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.424 |
| NlpD | ftsZ | XOO0513 | XOO3822 | Membrane proteins related to metalloendopeptidases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.449 |
| NlpD | hflB | XOO0513 | XOO2949 | Membrane proteins related to metalloendopeptidases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.423 |
| NlpD | htrB | XOO0513 | XOO0596 | Membrane proteins related to metalloendopeptidases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Lipid A biosynthesis lauroyl acyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.404 |
| NlpD | htrB-2 | XOO0513 | XOO0925 | Membrane proteins related to metalloendopeptidases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). | 0.404 |
| NlpD | lepB | XOO0513 | XOO1853 | Membrane proteins related to metalloendopeptidases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Signal peptidase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the peptidase S26 family. | 0.462 |
| NlpD | mrcA | XOO0513 | XOO1156 | Membrane proteins related to metalloendopeptidases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Penicillin-binding protein 1A; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.534 |
| amiC-2 | NlpD | XOO2733 | XOO0513 | N-acetylmuramoyl-L-alanine amidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Membrane proteins related to metalloendopeptidases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.431 |
| anmK | NlpD | XOO0512 | XOO0513 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Membrane proteins related to metalloendopeptidases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.744 |
| dniR-2 | NlpD | XOO3266 | XOO0513 | Membrane-bound lytic murein transglycosylase D precursor; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Membrane proteins related to metalloendopeptidases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.422 |
| dxr | NlpD | XOO1970 | XOO0513 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Membrane proteins related to metalloendopeptidases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.424 |
| ftsZ | NlpD | XOO3822 | XOO0513 | Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Membrane proteins related to metalloendopeptidases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.449 |
| ftsZ | hflB | XOO3822 | XOO2949 | Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.580 |
| ftsZ | lepB | XOO3822 | XOO1853 | Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Signal peptidase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the peptidase S26 family. | 0.515 |
| ftsZ | mrcA | XOO3822 | XOO1156 | Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Penicillin-binding protein 1A; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.545 |
| hflB | NlpD | XOO2949 | XOO0513 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Membrane proteins related to metalloendopeptidases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.423 |
| hflB | ftsZ | XOO2949 | XOO3822 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.580 |