| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PrsA | clpP | XOO3603 | XOO1033 | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.564 |
| PrsA | folA | XOO3603 | XOO3751 | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | Dihydrofolate reductase type III; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.700 |
| PrsA | gpV | XOO3603 | XOO1697 | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | Phage P2 baseplate assembly protein gpV; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.607 |
| PrsA | sppA | XOO3603 | XOO0573 | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | Protease IV; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.700 |
| XOO0571 | norM | XOO0571 | XOO0572 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Multidrug efflux protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.571 |
| XOO0571 | sppA | XOO0571 | XOO0573 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Protease IV; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.450 |
| XOO0592 | sppA | XOO0592 | XOO0573 | Predicted membrane protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Protease IV; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.447 |
| XOO2344 | sppA | XOO2344 | XOO0573 | Predicted transmembrane transcriptional regulator (anti-sigma factor); Putative; ORF located using Glimmer/Genemark. | Protease IV; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.410 |
| clpP | PrsA | XOO1033 | XOO3603 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.564 |
| clpP | folA | XOO1033 | XOO3751 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Dihydrofolate reductase type III; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.785 |
| clpP | gpV | XOO1033 | XOO1697 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Phage P2 baseplate assembly protein gpV; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.408 |
| clpP | sppA | XOO1033 | XOO0573 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Protease IV; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.741 |
| folA | PrsA | XOO3751 | XOO3603 | Dihydrofolate reductase type III; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.700 |
| folA | clpP | XOO3751 | XOO1033 | Dihydrofolate reductase type III; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.785 |
| folA | gpV | XOO3751 | XOO1697 | Dihydrofolate reductase type III; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Phage P2 baseplate assembly protein gpV; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.610 |
| folA | nrdB | XOO3751 | XOO0475 | Dihydrofolate reductase type III; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.432 |
| folA | sppA | XOO3751 | XOO0573 | Dihydrofolate reductase type III; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Protease IV; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.629 |
| gpV | PrsA | XOO1697 | XOO3603 | Phage P2 baseplate assembly protein gpV; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.607 |
| gpV | clpP | XOO1697 | XOO1033 | Phage P2 baseplate assembly protein gpV; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.408 |
| gpV | folA | XOO1697 | XOO3751 | Phage P2 baseplate assembly protein gpV; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Dihydrofolate reductase type III; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.610 |