| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NrdG | exsB | XOO1671 | XOO1679 | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | Transcriptional regulator; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.998 |
| NrdG | folE | XOO1671 | XOO4600 | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.684 |
| NrdG | ptps | XOO1671 | XOO0769 | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 6-pyruvoyl tetrahydrobiopterin synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.996 |
| NrdG | queF | XOO1671 | XOO4185 | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.946 |
| PhoD | folE | XOO4554 | XOO4600 | Phosphodiesterase/alkaline phosphatase D; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.910 |
| PhoD | folE2 | XOO4554 | XOO2367 | Phosphodiesterase/alkaline phosphatase D; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.900 |
| PhoD | phoA | XOO4554 | XOO3296 | Phosphodiesterase/alkaline phosphatase D; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Alkaline phosphatase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the alkaline phosphatase family. | 0.971 |
| PhoD | phoD | XOO4554 | XOO4555 | Phosphodiesterase/alkaline phosphatase D; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Alkaline phosphatase D; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.959 |
| PhoD | ptps | XOO4554 | XOO0769 | Phosphodiesterase/alkaline phosphatase D; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 6-pyruvoyl tetrahydrobiopterin synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.900 |
| XOO0768 | ptps | XOO0768 | XOO0769 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 6-pyruvoyl tetrahydrobiopterin synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.634 |
| exsB | NrdG | XOO1679 | XOO1671 | Transcriptional regulator; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.998 |
| exsB | folE | XOO1679 | XOO4600 | Transcriptional regulator; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.581 |
| exsB | ptps | XOO1679 | XOO0769 | Transcriptional regulator; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 6-pyruvoyl tetrahydrobiopterin synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.974 |
| exsB | queF | XOO1679 | XOO4185 | Transcriptional regulator; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.991 |
| folE | NrdG | XOO4600 | XOO1671 | GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.684 |
| folE | PhoD | XOO4600 | XOO4554 | GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Phosphodiesterase/alkaline phosphatase D; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.910 |
| folE | exsB | XOO4600 | XOO1679 | GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Transcriptional regulator; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.581 |
| folE | folE2 | XOO4600 | XOO2367 | GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.924 |
| folE | hisI | XOO4600 | XOO2262 | GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase bifunctional enzyme; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the N-terminal section; belongs to the PRA-CH family. | 0.569 |
| folE | phoA | XOO4600 | XOO3296 | GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Alkaline phosphatase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the alkaline phosphatase family. | 0.900 |