| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MiaA | hflC | XOO2936 | XOO0913 | tRNA delta(2)-isopentenylpyrophosphate transferase; Transfers dimethylallyl groups to AMP as part of the biosynthesis of cytokinin. | Integral membrane proteinase subunit; HflC and HflK could regulate a protease. | 0.682 |
| MiaA | hflK | XOO2936 | XOO0912 | tRNA delta(2)-isopentenylpyrophosphate transferase; Transfers dimethylallyl groups to AMP as part of the biosynthesis of cytokinin. | Integral membrane protease subunit; HflC and HflK could encode or regulate a protease. | 0.676 |
| MiaA | hflX | XOO2936 | XOO2945 | tRNA delta(2)-isopentenylpyrophosphate transferase; Transfers dimethylallyl groups to AMP as part of the biosynthesis of cytokinin. | GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.757 |
| XOO1793 | hflC | XOO1793 | XOO0913 | Membrane protein implicated in regulation of membrane protease activity; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Integral membrane proteinase subunit; HflC and HflK could regulate a protease. | 0.537 |
| XOO1793 | hflK | XOO1793 | XOO0912 | Membrane protein implicated in regulation of membrane protease activity; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Integral membrane protease subunit; HflC and HflK could encode or regulate a protease. | 0.576 |
| cstA | grpE | XOO1447 | XOO2030 | Carbon starvation protein A; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.658 |
| cstA | hflC | XOO1447 | XOO0913 | Carbon starvation protein A; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Integral membrane proteinase subunit; HflC and HflK could regulate a protease. | 0.684 |
| cstA | hflK | XOO1447 | XOO0912 | Carbon starvation protein A; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Integral membrane protease subunit; HflC and HflK could encode or regulate a protease. | 0.681 |
| cstA | ohr | XOO1447 | XOO4456 | Carbon starvation protein A; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Organic hydroperoxide resistance protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.609 |
| grpE | cstA | XOO2030 | XOO1447 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Carbon starvation protein A; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.658 |
| grpE | hflB | XOO2030 | XOO2949 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.683 |
| grpE | hflC | XOO2030 | XOO0913 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Integral membrane proteinase subunit; HflC and HflK could regulate a protease. | 0.718 |
| grpE | hflK | XOO2030 | XOO0912 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Integral membrane protease subunit; HflC and HflK could encode or regulate a protease. | 0.720 |
| grpE | miaA | XOO2030 | XOO2947 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.481 |
| grpE | ohr | XOO2030 | XOO4456 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Organic hydroperoxide resistance protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.469 |
| hflB | grpE | XOO2949 | XOO2030 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.683 |
| hflB | hflC | XOO2949 | XOO0913 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Integral membrane proteinase subunit; HflC and HflK could regulate a protease. | 0.932 |
| hflB | hflK | XOO2949 | XOO0912 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Integral membrane protease subunit; HflC and HflK could encode or regulate a protease. | 0.965 |
| hflB | hflX | XOO2949 | XOO2945 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.820 |
| hflB | miaA | XOO2949 | XOO2947 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.756 |
