| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MiaA | hflC | XOO2936 | XOO0913 | tRNA delta(2)-isopentenylpyrophosphate transferase; Transfers dimethylallyl groups to AMP as part of the biosynthesis of cytokinin. | Integral membrane proteinase subunit; HflC and HflK could regulate a protease. | 0.682 |
| MiaA | hflK | XOO2936 | XOO0912 | tRNA delta(2)-isopentenylpyrophosphate transferase; Transfers dimethylallyl groups to AMP as part of the biosynthesis of cytokinin. | Integral membrane protease subunit; HflC and HflK could encode or regulate a protease. | 0.676 |
| MiaA | hflX | XOO2936 | XOO2945 | tRNA delta(2)-isopentenylpyrophosphate transferase; Transfers dimethylallyl groups to AMP as part of the biosynthesis of cytokinin. | GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.757 |
| MiaA | hfq | XOO2936 | XOO2946 | tRNA delta(2)-isopentenylpyrophosphate transferase; Transfers dimethylallyl groups to AMP as part of the biosynthesis of cytokinin. | Host factor-I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.557 |
| cstA | grpE | XOO1447 | XOO2030 | Carbon starvation protein A; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.658 |
| cstA | hflC | XOO1447 | XOO0913 | Carbon starvation protein A; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Integral membrane proteinase subunit; HflC and HflK could regulate a protease. | 0.684 |
| cstA | hflK | XOO1447 | XOO0912 | Carbon starvation protein A; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Integral membrane protease subunit; HflC and HflK could encode or regulate a protease. | 0.681 |
| cstA | ohr | XOO1447 | XOO4456 | Carbon starvation protein A; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Organic hydroperoxide resistance protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.609 |
| dnaK | grpE | XOO2031 | XOO2030 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.997 |
| dnaK | hflB | XOO2031 | XOO2949 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.779 |
| dnaK | hflC | XOO2031 | XOO0913 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Integral membrane proteinase subunit; HflC and HflK could regulate a protease. | 0.574 |
| dnaK | hflK | XOO2031 | XOO0912 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Integral membrane protease subunit; HflC and HflK could encode or regulate a protease. | 0.465 |
| dnaK | hfq | XOO2031 | XOO2946 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Host factor-I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.526 |
| grpE | cstA | XOO2030 | XOO1447 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Carbon starvation protein A; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.658 |
| grpE | dnaK | XOO2030 | XOO2031 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.997 |
| grpE | hflB | XOO2030 | XOO2949 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.683 |
| grpE | hflC | XOO2030 | XOO0913 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Integral membrane proteinase subunit; HflC and HflK could regulate a protease. | 0.718 |
| grpE | hflK | XOO2030 | XOO0912 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Integral membrane protease subunit; HflC and HflK could encode or regulate a protease. | 0.720 |
| grpE | miaA | XOO2030 | XOO2947 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.481 |
| grpE | ohr | XOO2030 | XOO4456 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Organic hydroperoxide resistance protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.469 |
