Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (418 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 0.994
pykA
Pyruvate kinase type II; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the pyruvate kinase family.
 
 
 0.950
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.943
cbbFC
Fructose-1,6-bisphosphatase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
    
 0.937
tktA
Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.936
fruK
1-phosphofructokinase (fructose 1-phosphate kinase); Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the carbohydrate kinase PfkB family.
  
  
 0.933
xanB
Phosphomannose isomerase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
 0.930
talB
Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
   
 0.928
XOO3412
Fructose-bisphosphate aldolase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class I fructose-bisphosphate aldolase family.
  
 0.922
scrK
Fructokinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 0.918
Your Current Organism:
Xanthomonas oryzae
NCBI taxonomy Id: 291331
Other names: X. oryzae pv. oryzae KACC 10331, Xanthomonas oryzae pv. oryzae KACC 10331, Xanthomonas oryzae pv. oryzae str. KACC 10331, Xanthomonas oryzae pv. oryzae strain KACC 10331
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