| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GloA | HemN | XOO1142 | XOO1140 | Lactoylglutathione lyase and related lyases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.758 |
| GloA | XOO1138 | XOO1142 | XOO1138 | Lactoylglutathione lyase and related lyases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.443 |
| GloA | XOO1139 | XOO1142 | XOO1139 | Lactoylglutathione lyase and related lyases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Transcriptional antiterminator; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.443 |
| GloA | XOO1141 | XOO1142 | XOO1141 | Lactoylglutathione lyase and related lyases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Ham1 like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.811 |
| GloA | XOO1144 | XOO1142 | XOO1144 | Lactoylglutathione lyase and related lyases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.579 |
| GloA | gmk | XOO1142 | XOO1145 | Lactoylglutathione lyase and related lyases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.400 |
| GloA | rph | XOO1142 | XOO1143 | Lactoylglutathione lyase and related lyases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.786 |
| GloA | soxR | XOO1142 | XOO1257 | Lactoylglutathione lyase and related lyases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Transcriptional regulator soxR family; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.408 |
| HemN | GloA | XOO1140 | XOO1142 | Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Lactoylglutathione lyase and related lyases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.758 |
| HemN | XOO1138 | XOO1140 | XOO1138 | Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.596 |
| HemN | XOO1139 | XOO1140 | XOO1139 | Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Transcriptional antiterminator; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.599 |
| HemN | XOO1141 | XOO1140 | XOO1141 | Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Ham1 like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.928 |
| HemN | XOO1144 | XOO1140 | XOO1144 | Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.660 |
| HemN | gmk | XOO1140 | XOO1145 | Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.505 |
| HemN | rph | XOO1140 | XOO1143 | Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.820 |
| XOO1138 | GloA | XOO1138 | XOO1142 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Lactoylglutathione lyase and related lyases; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.443 |
| XOO1138 | HemN | XOO1138 | XOO1140 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.596 |
| XOO1138 | XOO1139 | XOO1138 | XOO1139 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Transcriptional antiterminator; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.963 |
| XOO1138 | XOO1141 | XOO1138 | XOO1141 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Ham1 like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.584 |
| XOO1138 | XOO1144 | XOO1138 | XOO1144 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.430 |