| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XOO1288 | kdsA | XOO1288 | XOO2966 | Low specificity phosphatase (HAD superfamily); Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 2-dehydro-3-deoxyphosphooctonate aldolase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the KdsA family. | 0.991 |
| XOO1288 | kdsB | XOO1288 | XOO2295 | Low specificity phosphatase (HAD superfamily); Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.984 |
| XOO1288 | kdtA | XOO1288 | XOO0926 | Low specificity phosphatase (HAD superfamily); Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.664 |
| XOO1288 | kpsF | XOO1288 | XOO1289 | Low specificity phosphatase (HAD superfamily); Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | Polysialic acid capsule expression protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.991 |
| XOO1288 | lptA | XOO1288 | XOO1286 | Low specificity phosphatase (HAD superfamily); Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. | 0.899 |
| XOO1288 | lptC | XOO1288 | XOO1287 | Low specificity phosphatase (HAD superfamily); Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. | 0.924 |
| XOO1288 | lpxA | XOO1288 | XOO1965 | Low specificity phosphatase (HAD superfamily); Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.656 |
| XOO1288 | murA | XOO1288 | XOO1290 | Low specificity phosphatase (HAD superfamily); Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.661 |
| XOO1288 | rpoN | XOO1288 | XOO1284 | Low specificity phosphatase (HAD superfamily); Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.844 |
| XOO1288 | yhbG | XOO1288 | XOO1285 | Low specificity phosphatase (HAD superfamily); Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | ABC transporter ATP-binding protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.931 |
| kdsA | XOO1288 | XOO2966 | XOO1288 | 2-dehydro-3-deoxyphosphooctonate aldolase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the KdsA family. | Low specificity phosphatase (HAD superfamily); Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 0.991 |
| kdsA | kdsB | XOO2966 | XOO2295 | 2-dehydro-3-deoxyphosphooctonate aldolase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the KdsA family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.900 |
| kdsA | kdtA | XOO2966 | XOO0926 | 2-dehydro-3-deoxyphosphooctonate aldolase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.893 |
| kdsA | kpsF | XOO2966 | XOO1289 | 2-dehydro-3-deoxyphosphooctonate aldolase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the KdsA family. | Polysialic acid capsule expression protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.993 |
| kdsA | lpxA | XOO2966 | XOO1965 | 2-dehydro-3-deoxyphosphooctonate aldolase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the KdsA family. | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.879 |
| kdsA | yhbG | XOO2966 | XOO1285 | 2-dehydro-3-deoxyphosphooctonate aldolase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the KdsA family. | ABC transporter ATP-binding protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.444 |
| kdsB | XOO1288 | XOO2295 | XOO1288 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Low specificity phosphatase (HAD superfamily); Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 0.984 |
| kdsB | kdsA | XOO2295 | XOO2966 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 2-dehydro-3-deoxyphosphooctonate aldolase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the KdsA family. | 0.900 |
| kdsB | kdtA | XOO2295 | XOO0926 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.970 |
| kdsB | kpsF | XOO2295 | XOO1289 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Polysialic acid capsule expression protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.931 |