| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XOO1435 | lysA-2 | XOO1435 | XOO1433 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Diaminopimelate decarboxylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.905 |
| XOO1435 | murD | XOO1435 | XOO1436 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine. Belongs to the MurCDEF family. MurD2 subfamily. | 0.999 |
| XOO1435 | murE | XOO1435 | XOO3830 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.900 |
| argG | asd | XOO2675 | XOO3259 | Argininosuccinate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.475 |
| argG | hisI | XOO2675 | XOO2262 | Argininosuccinate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase bifunctional enzyme; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the N-terminal section; belongs to the PRA-CH family. | 0.803 |
| argG | lysA | XOO2675 | XOO1354 | Argininosuccinate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Diaminopimelate decarboxylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.848 |
| argG | lysA-2 | XOO2675 | XOO1433 | Argininosuccinate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Diaminopimelate decarboxylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.989 |
| argG | metL | XOO2675 | XOO2242 | Argininosuccinate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartokinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.929 |
| argG | thrB | XOO2675 | XOO2243 | Argininosuccinate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.417 |
| asd | argG | XOO3259 | XOO2675 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Argininosuccinate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.475 |
| asd | dapF | XOO3259 | XOO3997 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.506 |
| asd | hisI | XOO3259 | XOO2262 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase bifunctional enzyme; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the N-terminal section; belongs to the PRA-CH family. | 0.440 |
| asd | lysA | XOO3259 | XOO1354 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate decarboxylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.690 |
| asd | lysA-2 | XOO3259 | XOO1433 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate decarboxylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.990 |
| asd | metL | XOO3259 | XOO2242 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Aspartokinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.997 |
| asd | thrB | XOO3259 | XOO2243 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.691 |
| dapF | asd | XOO3997 | XOO3259 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.506 |
| dapF | lysA | XOO3997 | XOO1354 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Diaminopimelate decarboxylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.962 |
| dapF | lysA-2 | XOO3997 | XOO1433 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Diaminopimelate decarboxylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.967 |
| dapF | metL | XOO3997 | XOO2242 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Aspartokinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.573 |