| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XOO0329 | pqqC | XOO0329 | XOO1734 | Polyvinylalcohol dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | PqqC protein; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. | 0.529 |
| XOO0329 | pqqE | XOO0329 | XOO1733 | Polyvinylalcohol dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | PqqE protein; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). | 0.552 |
| XOO0329 | pqqG | XOO0329 | XOO1735 | Polyvinylalcohol dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Pyrroloquinoline quinone biosynthesis protein G; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family. | 0.527 |
| XOO1323 | glyA | XOO1323 | XOO3860 | 2-nitropropane dioxygenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.705 |
| XOO1323 | pqqC | XOO1323 | XOO1734 | 2-nitropropane dioxygenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | PqqC protein; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. | 0.649 |
| gltB | glyA | XOO0177 | XOO3860 | Glutamate synthase, alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.580 |
| gltB | nodQ | XOO0177 | XOO3396 | Glutamate synthase, alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | ATP sulfurylase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.672 |
| gltB | pqqC | XOO0177 | XOO1734 | Glutamate synthase, alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | PqqC protein; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. | 0.559 |
| gltB | pqqG | XOO0177 | XOO1735 | Glutamate synthase, alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Pyrroloquinoline quinone biosynthesis protein G; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family. | 0.564 |
| glyA | XOO1323 | XOO3860 | XOO1323 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 2-nitropropane dioxygenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.705 |
| glyA | gltB | XOO3860 | XOO0177 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glutamate synthase, alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.580 |
| glyA | pqqC | XOO3860 | XOO1734 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | PqqC protein; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. | 0.566 |
| moaA | pqqC | XOO1059 | XOO1734 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | PqqC protein; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. | 0.508 |
| nodQ | gltB | XOO3396 | XOO0177 | ATP sulfurylase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Glutamate synthase, alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.672 |
| nodQ | pqqC | XOO3396 | XOO1734 | ATP sulfurylase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | PqqC protein; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. | 0.544 |
| pqqC | XOO0329 | XOO1734 | XOO0329 | PqqC protein; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. | Polyvinylalcohol dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.529 |
| pqqC | XOO1323 | XOO1734 | XOO1323 | PqqC protein; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. | 2-nitropropane dioxygenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.649 |
| pqqC | gltB | XOO1734 | XOO0177 | PqqC protein; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. | Glutamate synthase, alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.559 |
| pqqC | glyA | XOO1734 | XOO3860 | PqqC protein; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.566 |
| pqqC | moaA | XOO1734 | XOO1059 | PqqC protein; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.508 |