| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MetA | XOO1819 | XOO1388 | XOO1819 | Homoserine trans-succinylase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.938 |
| MetA | cysB | XOO1388 | XOO0777 | Homoserine trans-succinylase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.827 |
| MetA | glyA | XOO1388 | XOO3860 | Homoserine trans-succinylase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.800 |
| MetA | ilvA | XOO1388 | XOO0228 | Homoserine trans-succinylase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | Threonine dehydratase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.822 |
| MetA | met | XOO1388 | XOO2093 | Homoserine trans-succinylase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-serine, forming succinyl-L-serine. | 0.900 |
| MetA | metA | XOO1388 | XOO1817 | Homoserine trans-succinylase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.900 |
| MetA | metB-2 | XOO1388 | XOO1818 | Homoserine trans-succinylase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | Cystathionine gamma-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.958 |
| MetA | metL | XOO1388 | XOO2242 | Homoserine trans-succinylase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | Aspartokinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.965 |
| MetA | pssA | XOO1388 | XOO0811 | Homoserine trans-succinylase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | Phosphatidylserine synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.800 |
| MetA | rtxA | XOO1388 | XOO1390 | Homoserine trans-succinylase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | RtxA; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.978 |
| XOO1819 | MetA | XOO1819 | XOO1388 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Homoserine trans-succinylase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.938 |
| XOO1819 | cysB | XOO1819 | XOO0777 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.822 |
| XOO1819 | met | XOO1819 | XOO2093 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-serine, forming succinyl-L-serine. | 0.939 |
| XOO1819 | metA | XOO1819 | XOO1817 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.929 |
| XOO1819 | metB-2 | XOO1819 | XOO1818 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Cystathionine gamma-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.972 |
| XOO1819 | metL | XOO1819 | XOO2242 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Aspartokinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.944 |
| XOO1819 | rtxA | XOO1819 | XOO1390 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | RtxA; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.846 |
| cysB | MetA | XOO0777 | XOO1388 | Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Homoserine trans-succinylase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.827 |
| cysB | XOO1819 | XOO0777 | XOO1819 | Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.822 |
| cysB | glyA | XOO0777 | XOO3860 | Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.949 |