| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PilE | era | XOO1854 | XOO1856 | Tfp pilus assembly protein PilE; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.843 |
| PilE | lepA | XOO1854 | XOO1852 | Tfp pilus assembly protein PilE; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | GTP binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.595 |
| PilE | lepB | XOO1854 | XOO1853 | Tfp pilus assembly protein PilE; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Signal peptidase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the peptidase S26 family. | 0.810 |
| PilE | recO | XOO1854 | XOO1857 | Tfp pilus assembly protein PilE; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | DNA repair protein; Involved in DNA repair and RecF pathway recombination. | 0.736 |
| PilE | rnc | XOO1854 | XOO1855 | Tfp pilus assembly protein PilE; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.872 |
| YidC | lepB | XOO4636 | XOO1853 | Preprotein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | Signal peptidase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the peptidase S26 family. | 0.704 |
| YidC | rnc | XOO4636 | XOO1855 | Preprotein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.621 |
| era | PilE | XOO1856 | XOO1854 | GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Tfp pilus assembly protein PilE; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.843 |
| era | lepA | XOO1856 | XOO1852 | GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | GTP binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.799 |
| era | lepB | XOO1856 | XOO1853 | GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Signal peptidase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the peptidase S26 family. | 0.847 |
| era | recO | XOO1856 | XOO1857 | GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | DNA repair protein; Involved in DNA repair and RecF pathway recombination. | 0.799 |
| era | rnc | XOO1856 | XOO1855 | GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.915 |
| gltB | lepA | XOO0177 | XOO1852 | Glutamate synthase, alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | GTP binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.771 |
| gltB | lepB | XOO0177 | XOO1853 | Glutamate synthase, alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Signal peptidase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the peptidase S26 family. | 0.708 |
| lepA | PilE | XOO1852 | XOO1854 | GTP binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Tfp pilus assembly protein PilE; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.595 |
| lepA | era | XOO1852 | XOO1856 | GTP binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.799 |
| lepA | gltB | XOO1852 | XOO0177 | GTP binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Glutamate synthase, alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.771 |
| lepA | lepB | XOO1852 | XOO1853 | GTP binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Signal peptidase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the peptidase S26 family. | 0.976 |
| lepA | recO | XOO1852 | XOO1857 | GTP binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | DNA repair protein; Involved in DNA repair and RecF pathway recombination. | 0.635 |
| lepA | rimO | XOO1852 | XOO3272 | GTP binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Conserved hypothetical protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.413 |